Injuries are important medical problems that may cause inflammation, oxidative stress, endocrine disorders, immune response, and hypermetabolic and catabolic responses which affect most organs in the body. Research has shown that CoQ10 may help subjects from certain injuries. Here, we are going to review a few articles on this topic:
Gulce Gel and colleagues investigated whether combining Coenzyme Q10 (CoQ10) and ozone therapy could help rats recover from spinal cord injuries. The study found that rats given both treatments showed better results than those given either treatment alone. This suggests a combined approach might offer neuroprotective benefits by reducing cell death and improving overall recovery based on various assessments.
Soleyman Bafadam and colleagues, on the other hand, studied a potential treatment for heart damage in older rats. When blood flow to the heart is blocked and then restored (reperfusion), it can cause further damage. Researchers examined if combining two treatments, mitochondrial transplantation (injecting healthy energy centers from cells) and CoQ10 (a coenzyme), could protect the heart muscle. They found that the combination improved heart function and reduced cell death compared to either treatment alone. This suggests that combining these approaches might be a promising strategy to protect the heart from damage caused by reperfusion injury, especially in older individuals.
Zahra Kiani and colleagues investigated whether CoQ10 supplements could help patients recover from burn injuries. The study found no significant improvements in inflammation, oxidative stress, or other key recovery markers. However, patients taking CoQ10 did show an increase in albumin, a protein important for various bodily functions. More research is needed to confirm this effect and understand its potential benefits.
REFERENCE
1. Gulce Gel et al, Neuroprotective Effects Of Coenzyme Q 10 And Ozone Therapy On Experimental Traumatic Spinal Cord Injuries In Rats, World Neurosurg. 2024 Apr 27:S1878-8750(24)00715-0. doi: 10.1016/j.wneu.2024.04.141.
2. Soleyman Bafadam et al,Mitochondrial transplantation combined with coenzyme Q10 induces cardioprotection and mitochondrial improvement in aged male rats with reperfusion injury, Exp Physiol. 2024 Mar 13. doi: 10.1113/EP091358.
3. Zahra Kiani et al, Coenzyme Q10 supplementation in burn patients: a double-blind placebo-controlled randomized clinical trial, Randomized Controlled Trial Trials. 2024 Mar 2;25(1):160.