Five health supplements may slow cognitive decline.

 While there's no single "cure-all" supplement for dementia, several options have shown promise in supporting cognitive function and potentially slowing cognitive decline. Here are 5 supplements that might be beneficial, but remember to consult a doctor before starting any new regimen:

1. Omega-3 Fatty Acids: Found in fatty fish like salmon and tuna, omega-3s possess anti-inflammatory properties that can help protect brain cells from damage and reduce inflammation, both of which contribute to dementia development. Studies suggest that individuals with higher omega-3 intake have a lower risk of dementia and slower cognitive decline.
2. Vitamin D: Crucial for brain health and nerve function, vitamin D deficiency is linked to an increased risk of dementia. Ensuring adequate vitamin D levels through sun exposure, diet, or supplements may improve cognitive function or      potentially slow cognitive decline.
3. B Vitamins: Particularly vitamins B6, B9 (folate), and B12, these B vitamins play essential roles in brain function and homocysteine metabolism. Homocysteine is an amino acid with high levels linked to an increased risk of dementia. B vitamin supplementation can help lower homocysteine levels and potentially reduce dementia risk.
4. Curcumin: The active compound in turmeric, curcumin has potent anti-inflammatory and antioxidant properties. Studies suggest it might improve cognitive function, reduce inflammation in the brain, and protect brain cells from damage, potentially slowing dementia progression.
5. Phosphatidylserine: A phospholipid naturally present in the brain, phosphatidylserine supports cell membrane function and communication between brain cells. Thus, it might improve memory, learning, and overall cognitive function, potentially benefiting individuals with early dementia. However, more studies are needed to clarify this point.

Remember, these supplements are not a guaranteed way to prevent or cure dementia. They should be used alongside a healthy lifestyle that includes a balanced diet, regular exercise, mentally stimulating activities, and quality sleep. Consult a doctor to determine the best approach for your individual needs and preferences.

Reference

Bao-Zhen Wei et al, The Relationship of Omega-3 Fatty Acids with Dementia and Cognitive Decline: Evidence from Prospective Cohort Studies of Supplementation, Dietary Intake, and Blood Markers Am J Clin Nutr. 2023 Jun;117(6):1096-1109.

Nithila Mariam Roy et al, Impact of vitamin D on neurocognitive function in dementia, depression, schizophrenia and ADHD, Front Biosci (Landmark Ed). 2021 Jan 1;26(3):566-611.

Zhibin Wang et al, B vitamins and prevention of cognitive decline and incident dementia: a systematic review and meta-analysis, Nutr Rev. 2022 Mar 10;80(4):931-949.

Abid Bhat et al, Benefits of curcumin in brain disorders Biofactors. 2019 Sep;45(5):666-689.doi: 10.1002.

Dimitra Sokolova et al, Insight into the role of phosphatidylserine in complement-mediated synapse loss in Alzheimer's disease, Fac Rev. 2021 Feb 24:10:19.